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13 days old

Associate Scientist II

Kelly Services
Bridgewater, NJ 08807
**Kelly Services is seeking an Associate Scientist II for a permanent role in Bridgewater, NJ**


The Associate Scientist II, Biology is responsible for conducting scientific experiments that contribute to preclinical research and drug discovery activities at our client's Gene Therapy group. The incumbent will perform production, purification, and characterization of recombinant adeno-associated viral (AAV) vectors to support in vivo efficacy and safety study in animals and will participate in the development of new methods and optimization of the existing methods for AAV production in-house. The incumbent is also responsible for communicating experimental results to his/her supervisor and the project team, and for maintaining AAV database.


The Associate Scientist II, Biology supports adherence to all regulatory requirements and company Standard Operating Procedures (SOPs) including as appropriate.


**Job Description:**


**ESSENTIAL FUNCTIONS**


_Primary duties/responsibilities:_


+ Under minimal supervision, executes experiments as directed by the supervisor and communicates results as part of multi-disciplinary team(s). May also design and conduct independent research experiments.

+ Analyzes experimental data using analytical software such as GraphPad Prism, Excel, etc.

+ Applies relevant scientific principles and techniques to research problems.

+ Maintains detailed laboratory notebooks.

+ Maintains broad knowledge of state-of-the-art principles and techniques and may contribute to the identification of new targets or technologies.

+ Presents findings internally and externally and contributes to the publication of the work of the project team in well-established and peer reviewed journals, subject to internal scientific and legal approval.

+ May provide technical and scientific input to the project team or research leadership.

+ Contributes to the development of patent applications as appropriate.

+ Complies with all safety requirements.

+ Contributes to general lab operations such as:

+ Equipment maintenance.

+ Identification of capital equipment needs

+ Maintenance of clean and uncluttered work areas

+ Maintain Inventory and order supplies as needed.


**Specific duties may also include, but may not be limited to, the following:**


+ Uses in-house established methods to produce rAAV vectors for in vivo efficacy and pharmacology studies.

+ Leads development of new methods and optimization of the existing methods for AAV production in-house.

+ Performs characterization of the produced rAAV vectors, including determining the titer, purity, and the transduction activity of the produced vectors.

+ Maintains database of AAV and plasmid vectors.

+ Performs general lab duties as assigned.


**KNOWLEDGE/SKILLS/ABILITIES REQUIRED**


? _* Minimum level of education and years of relevant work experience._


+ Bachelors degree in a biological scientific discipline with a minimum of 4 years experience or Masters degree in a biological scientific discipline and a minimum of 2 years relevant experience.


_* Special knowledge or skills needed and/or licenses or certificates required._


+ In depth knowledge of Cell biology and Molecular biology.

+ Mammalian cell culture maintenance and cryopreservation.

+ DNA and RNA purification and quantification, molecular cloning, PCR, RT-PCR, qPCR.

+ DNA and RNA transfection.

+ Western blotting, ELISA, HTRF, reporter assays.

+ Working knowledge of NGS sequencing.

+ Ability to work with LIMS and databases.

+ Demonstrates high technical proficiency, scientific creativity, independent thought, and the ability to collaborate with others on cross functional teams in a fast-paced, matrixed, environment consisting of internal and external team members.

+ Possesses knowledge of scientific principles and concepts and keeps current with relevant scientific literature.

+ Proficiency with Microsoft Office- Excel, Word, PowerPoint and GraphPad Prism.

+ Effective verbal and written communication and skills.

+ Analytical thinker with problem-solving skills and the ability to adapt to changing priorities and deadlines.

+ Effective planning, organization and time management skills including the ability to support and prioritize multiple projects.


_*Special knowledge or skills and/or licenses or certificates preferred._


+ Knowledge of AAV methodology is a strong plus.

+ Knowledge of bioinformatics is a strong plus.

+ ddPCR knowledge is a plus.


**APPLY NOW!**

**For immediate Consideration, please email your resume to paula.picard@kellyscientific.com**


**\#P1**


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **Science & Clinical?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the worlds most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goalsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kellys Human Resource Knowledge Center.
Kelly complies with the requirements of Californias state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.
Posted: 2022-09-16 Expires: 2022-10-17

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Associate Scientist II

Kelly Services
Bridgewater, NJ 08807

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