14 days old

Principal Scientist/Director

Kelly Services
San Diego, CA 92108
**Title:** Principal Scientist/Director

**Location:** San Diego, CA

**Job Summary:**

We are seeking an experienced, highly motivated and committed Principal Scientist/Director to join our growing team. The successful candidate will provide project leadership and hands-on experimentation to drive our cutting-edge oligonucleotide-based drug discovery programs. The role requires working in close partnership with our internal Chemistry, Bioanalytical and Bioassay teams, and external CROs to achieve our drug discovery objectives. The incumbent will have a track record of leading drug discovery projects and must have the ability to multi-task and function effectively in a fast-paced environment.


+ Provide scientific and strategic leadership to project teams to advance drug discovery programs.

+ Lead a team of internal scientists, contribute to, and provide oversight of experimental design, execution, integrated data analysis, and interpretation.

+ Contribute to the advancement of programs by developing cell-based assays and by designing in vitro and in vivo studies that support the SAR studies and mechanistic understanding of therapeutic targets.

+ Collaborate closely with project teams to achieve drug discovery goals and objectives.

+ Manage external CROs interactions to ensure high quality in vivo pharmacology data packages.

+ Interpret, summarize, and present research findings at internal and external scientific meetings.

+ Maintain a current knowledge of relevant literature, competitive landscape, and methodologies specific to oligonucleotide-based therapeutics.


+ PhD in Cellular and Molecular Biology or related scientific discipline with post-doctoral experience.

+ 10+ years with 3+ years experience leading drug discovery projects in an industry setting (pharma/biotech) required.

+ Advanced molecular, biochemical, and cellular skills set and proven track record designing and executing in vitro cellular and molecular assays to drive drug discovery projects.

+ Experienced in delivering high quality data packages for drug candidate selection.

+ Experience identifying, selecting, and managing preclinical CROs is a plus.

+ Disease area knowledge in neuroscience, hepatic or metabolic disease is a plus.

+ Experience working with oligonucleotides and RNAi is a plus.

+ Ability to lead, mentor and work as part of a team with a drive to partner effectively with internal leaders.

+ Self-motivated with excellent interpersonal, organizational and communication skills with the ability to work effectively in a dynamic and collaborative, fast-paced environment.


+ Pay commensurate with experience 401k with company match

+ Medical, Dental, Vision, Life Insurance, FSA, Employee Discounts

+ Performance based bonuses PTO and Holidays

**Work authorization:**

United States Required Background Check

**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.

**Why Kelly** **** **?**

Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.

**About Kelly** ****

At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.

Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (
Posted: 2022-01-07 Expires: 2022-02-10

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Principal Scientist/Director

Kelly Services
San Diego, CA 92108

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