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15 days old

Protein Scientist- Display Technologies

Kelly Services
San Carlos, CA 94070
Protein Scientist- Display Technologies


San Mateo, CA


Direct Hire


Job Description:


The Protein Scientist, Display Technologies is responsible for further extending capabilities for the high-throughput screening of antibodies. This is a direct-hire, Mon-Fri role during normal working hours.


Job responsibilities:


+ Lead the onboarding of phage and/or yeast display technology, including vector sourcing, panning and de-selection strategy development, and screening methods selection

+ Execute campaigns for lead optimization, humanization, and affinity maturation

+ Collaborate with Data Science and Machine Learning teams on strategic library design based around ML models designed to improve antibody biophysics

+ Develop display-compatible protein binding assays such as FACS, SPR/BLI, and ELISAs

+ Analyze and interpret high-throughput sequencing datasets

+ Innovate and establish new display technologies to address challenging targets, novel drug formats, and maximize the potential of the platform


Preferred qualifications:


+ PhD in a biology- or biochemistry-related discipline and at least 2 years of hands-on experience in phage or yeast display, preferably in an industry setting

+ Knowledge of the latest tools and technologies related to display-based antibody selection and screening, including strategies utilized to select for antibodies with desired affinity, stability, and activity profiles

+ Hands-on experience in display-related molecular biology techniques including PCR, cloning, library preparation and NGS sequence interpretation

+ Demonstrated experience designing and implementing high-throughput molecular biology workflows to facilitate the conversion of hits from sequence to bacteria- or mammalian-cell expressible drug formats

+ Ability to multi-task, work cross-functionally as a team, and train junior team members

+ Thrives in a fast-paced, dynamic start-up environment and enjoys building capabilities from the ground up

+ Nice-to-haves include experience with cell-free protein extracts, protein structural analysis tools, or automation


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)
Posted: 2021-10-06 Expires: 2021-11-06

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Protein Scientist- Display Technologies

Kelly Services
San Carlos, CA 94070

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