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21 days old

Research Scientist - Downstream Protein Purification Lead

Kelly Services
Greenfield, IN 46140
Kelly Science is seeking a **Research Scientist -Downstream Protein Purification Lead** for a leading company located in **Greenfield, IN.**


This opportunity offers **relocation assistance!**


**Shift:** 9:00am-5:00pm


**Employment Type:** Direct Hire; Full Time


**Summary:**


The Research Scientist is a laboratory-based position that requires mentorship and management of a small team of associate scientists who are responsible for throughput purification of protein-based drug hits and leads. The position will also require routine interaction with senior scientists across multiple discovery and core research laboratories.


**Job duties may include:**


+ Managing the entire protein purification workflow and working collaboratively with other colleagues to assess the functional properties of these purified biologic drug candidates.

+ participate in biotherapeutic molecule discovery efforts in the Research and Breakthrough Innovation Laboratories by performing small and medium-scale chromatography-based protein purification efforts to support both iterative molecular engineering efforts ,as well as preparing small amounts of biologic drugs for pilot in vivo studies.

+ Establish protein purification workflows to support single (AKTA) and parallel purification (automated parallel purification instrumentation) of biologic hit and lead molecules

+ Utilize FPLC chromatography with myriad resins / purification modalities incl. IEX, SEC, and affinity chromatography e.g., Ni-NTA, Protein A/G, Streptactin

+ Concentrate and buffer exchange protein containing solutions via automated HF and TFF instrumentation e.g., Akta Flux or Spectrum hardware

+ Analyze purity and quantity (concentration) of protein containing solutions before and after purification via SDS-PAGE, capillary electrophoresis, BLI, or western blot

+ Mentor and Supervise at least one Associate-level protein purification scientist

+ Demonstrate proficiency at data reporting, interpretation, and trending.

+ Demonstrate good documentation skills with regard to raw data recording and protocol authoring


**Qualifications:**


+ Ph.D or MS degree in a relevant scientific discipline (molecular biology, microbiology, cell biology, immunology, or biochemistry)

+ At least 2 years of experience working on R&D projects in the human or animal health industries.

+ Demonstrated practical experience in a wide variety of chromatographic based protein purification modalities

+ Experience with parallelization of medium to high throughput protein purification workflows

+ Effective oral and written communications skills.

+ High personal ethical and quality standards.

+ Exceptional problem solving and decision-making skills.

+ Must be able to work productively in an interdisciplinary team environment


**Interested? Apply today for immediate consideration!**


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)

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Posted: 2022-06-06 Expires: 2022-07-07

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Research Scientist - Downstream Protein Purification Lead

Kelly Services
Greenfield, IN 46140

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