JobWatch

1+ months

Scientist, CAR-T Preclinical Research

Kelly Services
Arcadia, CA 91007
**Kelly Science and Clinical** is the worlds most recognized brand in science and clinical staffing with more than 100 locations in North America, Europe, and the Pacific Rim. Our scientists contribute to the research and development of the next generation of small molecule drugs, biologics and cellular therapies.


**Overview**


We are seeking a Scientist for one of our clients, a startup biotechnology company that specializes in manufacturing cell and gene therapies for cancer patients around the world. Their innovative cGMP facility offers comprehensive end to end manufacturing and testing capabilities for clinical and commercial purposes. The incumbent will develop T cell-based immunotherapies to treat hematologic malignancies and solid tumors. Candidate is expected to work across the various aspects of preclinical development and validation of novel T cell / antibody therapeutics. The successful candidate has extensive experience in a combination of skills including, genetic manipulation of T cells and tumor cells using viral/nonviral methods, VCN determination using qPCR/ddPCR, T/NK cell isolation, optimization of culture conditions, immunophenotyping, development and optimization of a variety of assays (molecular, cell based, biochemical, immunological) for preclinical validation of cell therapy products


**Responsibilities**


+ Lead planning, design, and execution of experiments related of development and characterization of cellular immunotherapy products in coordination with R & D director.

+ Analyze, and report complex data to cross functional teams in a clear and concise manner

+ Mentor and train scientific staff on technical skills required to effectively perform experiments and to facilitate progression of projects

+ Manage multiple research projects simultaneously with the R & D team and collaborate with other departments (Process Science, Analytical Science, Quality, Manufacture) as necessary.

+ Contribute to various preclinical projects within R& D and those required by clients through in-depth scientific knowledge and demonstrated experience in analytical methods used in cellular immunotherapy field

+ Performs a wide range of non-routine exploratory experiments as required

+ Maintain precise laboratory notebooks, electronic records following high standards of data quality and integrity.

+ Prepare scientific/technical reports, summaries, protocols, etc, and present them to internal and external stakeholders.

+ Constantly improvise research strategies and adopt technologies to stay upfront in the field of immunotherapy


**Qualifications:**


+ Ph. D in the field of Immunology, Cell biology, Virology or Cancer biology or related life science discipline with 3+ years (Scientist) or 5+ years (Senior Scientist) or masters degree with 7 + years relevant research experience in Immunology/Cancer biology.

+ In depth scientific and technical understanding of cellular immunotherapy and tumor immunology.

+ 2+ years of managing research laboratory research team/associates in immunotherapy or cancer biology or relevant research projects is required for senior scientist level.

+ Prior research experience in antibody therapies, bispecific antibodies, and cellular therapies preferred

+ Demonstrated ability to independently design, plan and troubleshoot experiments, interpret results, and present to the R&D team and external clients.

+ Self-motivated and creative, able to work within a team and collaborate with external teams as needed to accomplish project objectives and deliverables.

+ Possess ability to identify problems early, technically trouble shoot and resolve challenges in early development and preclinical validation of CAR-T products.

+ Understands the importance of data integrity to enable a smooth transition of discovery research to manufacture and clinical trials.

+ Familiarity with FDA regulation of biologics and cell therapy products, IND-filing, GLP/GMP process is a plus.

+ Ability to stay organized, prioritize tasks, manage time efficiently, and provide creative solutions to meet program needs

+ Excellent interpersonal, verbal, and written communication skills

+ Comfortable working in a fast-paced startup environment and flexible to adjust workload based upon changing priorities

+ A strong academic research experience evidenced by high caliber publications in peer-reviewed journals is preferred

+ Intellectually curios candidates with passion for innovation and discovery research are welcome


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)
Posted: 2022-03-28 Expires: 2022-05-30

Before you go...

Our free job seeker tools include alerts for new jobs, saving your favorites, optimized job matching, and more! Just enter your email below.

Share this job:

Scientist, CAR-T Preclinical Research

Kelly Services
Arcadia, CA 91007

Join us to start saving your Favorite Jobs!

Sign In Create Account
Powered ByCareerCast