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19 days old

Senior Scientist -Antibody Cytokine Engineering

Kelly Services
Vancouver, WA 98661
**Kelly Services is actively recruiting for a Direct Hire opportunity for a Senior Scientist - Antibody Cytokine Engineering in Vancouver, Washington.**


The Senior Scientist will report to the Senior Research Fellow of R&D and will work on developing antibody and cytokine expression and engineering capabilities. The ideal candidate has extensive experience in antibody and cytokine expression and engineering, synthetic biology, DNA library design and construction. The successful candidate will apply theoretical, technical and hands-on expertise in antibody and cytokine expression and engineering to identify improved variants with desired attributes. The ideal candidate is highly motivated, pragmatic, self-directed, extremely organized, has excellent collaboration skills, a creative approach to problem-solving, and can execute nimbly and efficiently in a dynamic fast-paced environment.


**Responsibilities of the Sr. Scientist includes:**


+ Lead antibody and cytokine expression and engineering efforts using state-of-the-art technologies for library construction, selection and screening to obtain high performing antibody and cytokine variants.

+ Design/execute overall antibody and cytokine expression and engineering strategies.

+ Establish in-house processes for random and semi-random/rational mutagenesis library design and construction.

+ Perform antibody and cytokine library screening and selection to isolate optimized variants with drug-like properties.

+ Independently perform complex experiments with strong attention to quality, detail and documentation.

+ Interpret data, troubleshoot experiments and present work at both internal external meetings.

+ Proactively interact and effectively collaborate with team members from cross-functions.


**Qualifications of the Sr. Scientist includes:**


+ **Ph.D. Degree in Molecular Biology, Biochemistry or a related discipline with emphasis on antibody and cytokine expression and engineering with 3-5 years industry experience. (Master's Degree candidates with exception antibody and cytokine experience may also be considered.)**

+ Demonstrated success in delivering on antibody and cytokine expression and engineering programs under tight timelines.

+ Strong in-depth knowledge of antibody and cytokine biology as well as extensive hands-on experience in antibody and cytokine library design, construction, selection and screening.

+ Experience utilizing structural modeling and sequence analysis software for antibody and cytokine optimization to confer drug-like attributes.

+ Strong understanding of antibody and cytokine folding and the role of molecular chaperones.

+ Proven track record of strong problem-solving and troubleshooting skills.

+ Passion for building a gritty and creative company culture that is collaborative, multidisciplinary, and determined to make a transformative impact to our industry.

+ Extensive, hands-on experience using modern cloning techniques for DNA construction e.g., Gibson Assembly, Golden Gate Cloning, etc., preferred.

+ Experience using NGS technologies preferred.

+ Experience with high-throughput workflows, laboratory automation, and complex data sets preferred.

+ Experience and knowledge in protein purification and characterization preferred.

+ Experience with phage display and/or other molecular evolution technologies preferred.

+ Prior experience with various drug formats involving antibodies and cytokines is a huge plus.


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)
Posted: 2022-06-08 Expires: 2022-07-09

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Senior Scientist -Antibody Cytokine Engineering

Kelly Services
Vancouver, WA 98661

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