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1+ months

Senior Scientist, Computational Chemistry

Kelly Services
South San Francisco, CA 94080
PLEASE NOTE: Must be authorized to work lawfully in the United States for any employer without sponsorship.


Kelly Science & Clinical is seeking a Senior Scientist, Computational Chemistry to join their team in South San Francisco, CA/Remote for a leading China-based Contract Research Organization specializing in drug discovery services. For immediate consideration, please email your resume directly to Regan.Brown@KellyServices.com as well as apply online.


**Title: Senior Scientist, Computational Chemistry**


**Location: South San Francisco, CA/Remote**


**Direct Hire: Duration = Permanent (full-time/exempt/W-2)**


**Annual Salary: $140,000+/Year**


**Schedule/Shift: Monday Friday/1** **st**


**Estimated Start Date: 8/1/2022**


Exciting opportunity to play an important role at COMPANY, a leading China-based Contract Research Organization specializing in drug discovery services. With a team of over 2000 scientists, many pharmaceutical industry leaders, and experienced Pharmaceutical Executive Leadership at the helm, COMPANY is aligned and dedicated to technically and strategically accomplish the research initiatives of pharma and biotech companies from around the world.


We are looking for an experienced and innovative computational chemist to implement CADD tools that advance therapeutic discovery programs for our research partners. The successful candidate must have the drive and enthusiasm to act as an individual contributor or project leader for a number of projects simultaneously. He/She/They must also often act as the face of COMPANY to multiple international clients and be able to interact across disciplines and demonstrate technical prowess.


The position will be based at COMPANYs South San Francisco facility optimally, but we will consider strong candidates who can work effectively from a remote home office. Occasional trips to Shanghai, China may be necessary as well a travel within the United States to meet with clients/collaborators.


Responsibilities:


+ Provide computational chemistry support to SBDD or LBDD projects for clients primarily as part of a larger team or working individually to provide expert computational consultation.

+ Work closely with multiple major international biotechs, pharmaceutical companies, and academic institutions their drug discovery programs.

+ Independently plan, manage and perform research to support projects.

+ Contribute to a team charged with the identification of new drug discovery technologies to bring into COMPANY.

+ Investigate and promote novel computational methods such as AI and machine learning for clients efforts to accelerate certain stages of drug development.

+ Participate in efforts with Business Development to bring in new business by promoting COMPANYs computational technologies and expertise.

+ For a successful and talented candidate there will be opportunities for leadership within the team on scientific initiatives, programs, and for the overall relationship with certain clients and academic partners.


Qualifications:


+ Requires a broadly trained computational chemist whose skills include:

+ Industrial experience in driving lead identification and lead optimization using computational chemistry techniques.

+ The ability to interpret and communicate structural information to medicinal chemists and proactively suggest ideas for potency or selectivity improvement within the MedChem design cycle.

+ Hands-on experience in the following areas: structure-based drug design including docking, homology modeling, molecular dynamics simulation, free energy perturbation; ligand-based drug design including pharmacophore modeling, QSAR, 3D-QSAR, pharmacophore- or shape-based database searching, combinatorial library design, target focused library construction, R-group decomposition, pairwise matching, cliff analysis.

+ Familiarity with state-of-the-art modeling and cheminformatics tools such as Maestro, MOE, JChem, Vortex, PyMOL, Spotfire, KNIME, and BioLuminate.

+ Ph.D. and post-doctoral experience as well as a track record of technical excellence as shown by peer reviewed publications and inventorship status on patents.

+ 4 years or more of pharma/biotech experience with a focus on computational chemistry.

+ Must be a team player with strong project leadership skills and a demonstrated ability to deliver results.

+ Must understand the goals of project teams, timelines and deliverables and help ensure that resourcing is on-track to meet these goals.

+ Strong communication skills with the ability to effectively describe results and ideas to clients who may be based all over the world.

+ The ability to communicate in Mandarin is advantageous but is not required.


**Apply today!**


**Refer a friend!**


*Available for purchase and administered by a designated third-party vendor. (3/140,0/20/28,0)


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)
Posted: 2022-07-11 Expires: 2022-09-05

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Senior Scientist, Computational Chemistry

Kelly Services
South San Francisco, CA 94080

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