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1+ months

Sr. Research Scientist, siRNA/mRNA Design and Drug Discovery

Kelly Services
San Diego, CA 92108
**Title:** Sr. Research Scientist, siRNA/mRNA Design and Drug Discovery


**Location:** San Diego, CA


**Job Overview:**


We are currently seeking a talented, highly motivated and independent research scientist with extensive bioinformatics and RNA design experience to join our R&D team. The successful candidate is expected to lead the efforts of siRNA/mRNA drug design, to evaluate the activities of the newly designed RNA drugs in different biological systems, and, as one of key team members, to be actively engaged in the drug discovery activities to address unmet medical needs.


**Major Job Functions:**


+ Lead the efforts on design, modification and optimization of siRNA and/or mRNA drugs for different therapeutic programs

+ Evaluate the activities of the siRNA and/or mRNA drugs using appropriate biological systems, screen and identify the leads

+ Develop novel approaches for siRNA and/or mRNA modifications for potential drug development

+ Mine tangible drug targets from public databases and propose to drug discovery team

+ Present research progress internally and externally and write study reports.

+ Contribute to preparation of IP and IND filings

+ Work closely with cross-functional team members on multiple projects simultaneously


**Education and Experience Requirements:**


+ Ph.D. in biology or chemistry with at least 8 years of therapeutic siRNA and/or mRNA design experience and established knowledge in the area of design of pharmacologically active siRNA and/or mRNA

+ Deep knowledge of related public databases, algorithm and tools/software

+ Demonstrated expertise in functional genomics, molecular phenotypic profiling, and chemistry

+ Thorough knowledge of working with siRNA and/or mRNA screening.

+ A good understanding of the basic pharmacology principles of nucleic acid therapies in term of their efficacy, pharmacokinetics and toxicity

+ Demonstrated innovation with track record in molecular design of novel RNA therapeutics with an ability to be creative and take a proactive approach to problem-solving

+ Ability and desire to work collaboratively on inter-disciplinary projects that span the chemical, analytical, formulation, and biological sciences

+ Strong publications in peer-reviewed scientific journals

+ Proven interpersonal and written/oral communication skills

+ Level of the position is flexible and commensurate based on candidate s experience


**Physical Job Requirements:**


+ Mandatory Covid-19 vaccination policy in effect.

+ Office/Lab environment.

+ Lifting to 20 pounds may be required.

+ While performing the duties of this job, the employee is regularly required to use their hands and fingers to operate a computer keyboard, mouse, and telephone keypad or to write, as well as talk and hear.

+ They are required to stand, walk or sit, reach with hands and arms, stoop, kneel, crouch or crawl.

+ Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and ability to focus.


**_For immediate consideration apply today!_**


**_Questions? Please reach out to Jessica at jessica.rubano@kellyscientific.com_**


**You should know:** Your safety matters! Vaccination against COVID-19 may be a requirement for this job in compliance with current client and governmental policies. A Kelly recruiter will confirm and share more details with you during the interview process.


**Why Kelly** **** **?**


Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire talented people just like you. Every day, we match science professionals with dream jobs that fit their skills and interestsits the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background/education in science, so we know a thing or two about the science market and how to get you noticed.


**About Kelly** ****


At Kelly, were always thinking about whats next and advising job seekers on new ways of working to reach their full potential. In fact, were a leading advocate for temporary/nontraditional workstyles, because we believe they allow flexibility and tremendous growth opportunities that enable a better way to work and live (plus, did we mention we provide a ton of benefits ?). Connecting great people with great companies is what we do best, and our employment opportunities span a wide variety of workstyles, skill levels, and industries around the world.


Kelly is an equal opportunity employer committed to employing a diverse workforce, including, but not limited to, minorities, females, individuals with disabilities, protected veterans, sexual orientation, gender identity. Equal Employment Opportunity is The Law. (https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm)

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Posted: 2022-03-04 Expires: 2022-06-04

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Sr. Research Scientist, siRNA/mRNA Design and Drug Discovery

Kelly Services
San Diego, CA 92108

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